Risk-stratification in normotensive acute pulmonary embolism

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Risk-stratification in normotensive acute pulmonary embolism

In the Netherlands, 10,000 to 12,500 patients per year are diagnosed with acute pulmonary embolism (PE) [1]. The large majority of these patients are normotensive. Just recently, the European Society of Cardiology (ESC) published an update of their guideline on the diagnosis and management of acute PE [2]. Compared with the previous version of 2008, special emphasis was given to risk stratifica...

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The prognostic value of copeptin, the C-terminal fragment of the precursor protein of vasopressin which is released upon stress, and hypotension in pulmonary embolism is unknown, especially if combined with biomarkers reflecting different pathophysiological axes such as myocardial injury (high-sensitivity troponin T (hsTnT)) and stretch (N-terminal pro-brain natriuretic peptide (NT-proBNP)).We ...

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Acute pulmonary embolism: part II: risk stratification, treatment, and prevention.

Pulmonary embolism (PE) presents with a wide clinical spectrum, from asymptomatic small PE to lifethreatening major PE that causes hypotension and cardiogenic shock (Table). Traditionally, our risk assessment is done by gestalt. However, a more precise risk assessment can be obtained by using a formal clinical scoring system, such as the Geneva Prognostic Index.1 The Geneva Prognostic Index use...

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Risk Stratification of Patients with Acute Pulmonary Embolism

Acute pulmonary embolism (PE) is an under-diagnosed but potentially fatal condition. This condition presents with a wide clinical spectrum, from asymptomatic small PE to lifethreatening one causing cardiogenic shock. Depending on the estimated risk of an adverse outcome, treatment with thrombolysis or embolectomy may be indicated in high-risk individuals. Conversely, early hospital discharge or...

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Article history: Received 5 June 2015 Accepted 20 June 2015 Available online 27 June 2015 over, laboratory testing showed elevated plasma concentrations of high-sensitivity troponin T (hsTnT, 65.8 ng/l; reference b14 ng/l [2]) and N-terminal pro-brain natriuretic peptide (NT-proBNP, 9024 pg/ml; reference b600 pg/ml [3]). Since the patient met all inclusion and no exclusion criteria, shewas incl...

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ژورنال

عنوان ژورنال: Netherlands Heart Journal

سال: 2014

ISSN: 1568-5888,1876-6250

DOI: 10.1007/s12471-014-0639-4